Cyclobenzaprine Flexeril Side Effects & Interactions

Initiation should begin with a 5 mg dose and slowly increased, under the careful eye of a doctor. These patients are generally more susceptible to drugs with potentially sedating effects, including cyclobenzaprine. FLEXERIL should be used with caution in subjects flexeril with tylenol with mild hepatic impairment starting with a 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of FLEXERIL in subjects with moderate to severe impairment is not recommended.

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It isn’t known exactly how this drug works to relax your muscles. It may decrease the signals from your brain that tell your muscles to spasm. Cyclobenzaprine also comes as an oral extended-release capsule. To view formulary information first create a list of plans.

Cyclobenzaprine (Flexeril) Uses, Side Effects, & Risks

Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Within the last five years, emergency room department visits related to muscle relaxant abuse almost doubled; they increased from 15,830 to 31,763 visits. How cyclobenzaprine (Flexeril) works is not well understood, but it helps alleviate stiffness, pain, and discomfort due to sprains, strains, or injuries to muscles. It is also sometimes prescribed off-label to treat fibromyalgia pain. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Not only will this provide an energy boost but it can also improve your mood and make it easier to fall asleep at night.

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As with all medications, the costs of cyclobenzaprine can vary. Cyclobenzaprine oral tablet may cause drowsiness and dizziness. This is more likely to happen in the few hours after you take it. Cyclobenzaprine may be used as part of combination therapy.

Interactions that can increase the effect of cyclobenzaprine

You and your doctor will work out the proper cyclobenzaprine dosage for your particular situation. However, in general, physicians will prescribe Flexeril dosages according to the guidelines below as provided by the Mayo Clinic. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions.

  • FLEXERIL may enhance the effects of alcohol, barbiturates, and other CNS depressants.
  • If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug.
  • As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment.
  • Cyclobenzaprine also has some sedative effects which may result in sleepiness and fatigue.

As of this writing, cyclobenzaprine isn’t FDA-approved for children younger than 15. The long-acting capsules are recommended for patients 18 years of age and older and come in 15 mg doses. Some patients may require two doses equaling 30 mg at one time or two 15 mg doses twice a day. Long-acting capsules are not recommended for anyone under the age of 18. Laboratory data were summarized, and mean change was presented for each numeric variable.

Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Recovered is not a medical, healthcare or therapeutic services provider and no medical, psychiatric, psychological or physical treatment or advice is being provided by Recovered. If you are facing a medical emergency or considering suicide or self harm, please call 911 immediately. Has been contributing to medical fields including mental health and addiction since she retired from medicine; with over 19 years of practicing clinical experience. Examples of drugs that can cause interactions with cyclobenzaprine are listed below.

Dose titration of CBP

Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of FLEXERIL in subjects with moderate to severe impairment is not recommended. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration. Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g. phenobarbital, phenytoin). Physostigmine is not recommended except to treat life-threatening symptoms that have been unresponsive to other therapies, and then only in close consultation with a poison control center.

Ask your healthcare professional how you should dispose of any medicine you do not use. If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce. Rinse the mouth to make sure all of the medicine have been swallowed.

Many insurance companies require prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

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